Mastering the innovative crafting systems in Resident Evil 9: Requiem requires a specialized approach, especially when playing as Grace Ashcraft. While Leon Kennedy follows a traditional system—automatically unlocking recipes as he acquires new weapons—Grace must actively conduct biological research to expand her arsenal.
Finding all Crafting Recipe locations is the only way to transform your harvested Infected Blood into the game's most potent munitions and survival tools. Securing every recipe is also a mandatory requirement for the "Master Craftsman" Trophy, which challenges you to craft every possible item in a single playthrough as Leon.
Early in the game, Grace unlocks recipes by finding Blood Specimens and analyzing them via the Laser Microscope minigame found in the Blood Lab. On the highest difficulty, an exclusive Insanity Blood Specimen is hidden within the Records Room. Analyzing it unlocks the recipe for the R.I.P. Knife and bulk Handgun Ammo.
Leon’s system is designed for speed and efficiency. He does not need to solve microscope puzzles; instead, his recipes are added to his inventory as soon as he acquires the relevant materials or firearms:
To use these recipes effectively, you must manage your raw resources and tool capacity:
Missing even one Blood Specimen can leave you without critical healing or firepower during the game's final descent. To prevent this, we have pinned every Crafting Recipe and Blood Specimen location on our RE9: Requiem Interactive Maps. Our map guides also provide the exact coordinates for the ID Wristbands needed to access locked labs. Use the links below to verify your progress.
| Name | Map Location | Details |
|---|---|---|
| Antique Coin ScrapARKAntique Coin Scrap | ARK | Found in the case on the cabinet. |
| Ink RibbonCare CenterInk Ribbon | Care Center | The Ink Ribbon Recipe is unlocked after you collect your first Ink Ribbon Tin. It is available only on Standard and Insanity difficulties. |
| Handgun Ammo x10East Raccoon CityHandgun Ammo x10 | East Raccoon City | Obtained automatically after picking up the Gunpowder (Small) in Logistics Warehouse 1F locker. |
| Machine Gun Ammo x40East Raccoon CityMachine Gun Ammo x40 | East Raccoon City | Obtained automatically after grabbing the Gal weapon from the silver case. |
| Molotov CocktailCare CenterMolotov Cocktail | Care Center | Found inside a case in the Bunkroom. |
| Mixed Herb (G+G)Care CenterMixed Herb (G+G) | Care Center | Obtained automatically through story progression in the Care Center. |
| Mixed Herb (G+G+G)Care CenterMixed Herb (G+G+G) | Care Center | Obtained automatically through story progression in the Care Center. |
| Makeshift KnifeCare CenterMakeshift Knife | Care Center | Obtained automatically through story progression in the Care Center. |
| ScrapCare CenterScrap | Care Center | Obtained automatically through story progression in the Care Center. |
| Handgun Ammo x8Care CenterHandgun Ammo x8 | Care Center | Unlocked by using the Blood Specimen (Denatured) on the Analyzer in the Blood Lab. |
| Hemolytic InjectorCare CenterHemolytic Injector | Care Center | Unlocked by using the Blood Specimen (Denatured) on the Analyzer in the Blood Lab. |
| Bottle of AcidARKBottle of Acid | ARK | Found in the case on the cabinet in the Monitor Control Room. |
| 12.7x55mm Ammo x2Care Center12.7x55mm Ammo x2 | Care Center | Obtained by using the Blood Specimen (Converged) on the Analyzer in the Blood Lab. Note: On Casual and Standard difficulties, the Converged Blood Specimen is found in the Waiting Room Closet, while on Insanity difficulty, it is found in the Records Room. |
| Med InjectorCare CenterMed Injector | Care Center | Obtained by using the Blood Specimen (Converged) on the Analyzer in the Blood Lab. Note: On Casual and Standard difficulties, the Converged Blood Specimen is found in the Waiting Room Closet, while on Insanity difficulty, it is found in the Records Room. |
| SteroidsCare CenterSteroids | Care Center | Obtained by using the Blood Specimen (Reversible) on the Analyzer in the Blood Lab. |
| StabilizerCare CenterStabilizer | Care Center | Obtained by using the Blood Specimen (Reversible) on the Analyzer in the Blood Lab. |
| Shotgun Shells x3Care CenterShotgun Shells x3 | Care Center | Automatically obtained after picking up the MSGB 500 weapon in the Attic. |
| Stacked Hand GrenadeCare CenterStacked Hand Grenade | Care Center | Automatically obtained after picking up your first Hand Grenade in the Attic. |
| Hand GrenadeCare CenterHand Grenade | Care Center | Automatically obtained after picking up your first Hand Grenade in the Attic. |
| Rifle Ammo x5Care CenterRifle Ammo x5 | Care Center | Obtained automatically when you get the Classic 70 on the Roof. |
| R.I.P. Knife (Insanity Difficulty Only)Care CenterR.I.P. Knife (Insanity Difficulty Only) | Care Center | Obtained by using the Blood Specimen (Polymerized) on the Analyzer in the Blood Lab. |
| Handgun Ammo x30 (Insanity Difficulty Only)Care CenterHandgun Ammo x30 (Insanity Difficulty Only) | Care Center | Obtained by using the Blood Specimen (Polymerized) on the Analyzer in the Blood Lab. |
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