Resident Evil Requiem Crafting Recipes are the foundation of both characters' survival systems — but Grace and Leon do not share a crafting system at all.
Every recipe, its unlock method, and its difficulty tag are tracked in MapMaster's checklist below, with locations pinned across the Care Center map, East Raccoon City, and the ARK map guide.
The complete resource index is at the Resident Evil Requiem interactive guide hub.
Grace runs a blood-based economy — she analyzes Blood Specimens on the Analyzer to unlock recipes, then physically harvests Infected Blood from the environment and corpses to craft anything.
It's slow, deliberate, and punishing if you miss a specimen early. Leon is the opposite — his recipes unlock automatically when he picks up new weapons or raw materials.
He just combines Scrap and Gunpowder. No puzzles, no blood, no lab work.
Grace's crafting depends on the Blood Collector tool, found in the Blood Lab in the Care Center East Wing.
It starts with a capacity of 100 units of Infected Blood. Before Grace can collect Infected Blood, she must obtain the Blood Collector from the Blood Lab. Once she has it, she can extract blood from environmental sources and corpses.
Open the Analyzer in the Blood Lab, run each Blood Specimen through the node puzzle, and the corresponding crafting recipe will unlock permanently.
The Denatured Specimen unlocks Handgun Ammo x8 and Hemolytic Injector crafting. The Converged Specimen unlocks Med Injector and 12.7x55mm Ammo.
The Reversible Specimen unlocks Steroids and Stabilizer. On Insanity, the Polymerized Specimen (Waiting Room Closet) additionally unlocks the R.I.P. Knife and Handgun Ammo x30.
All specimen locations and puzzle solutions are in the Blood Specimen guide.
Two recipes are found as readable documents and require no Analyzer puzzle.
Mixed Herb (G+G), Mixed Herb (G+G+G), Makeshift Knife, and Scrap recipes are available from the beginning of Grace's section.
For crafting priority, Hemolytic Injectors are the early MVP — they're the only reliable way to deal with the roaming East Wing monster, and you need three of them.
After that, stockpile Handgun Ammo and save Empty Injectors for Steroids or Stabilizers, depending on your playstyle. Molotov Cocktails become essential for crowd control once unlocked.
The Blood Collector's 100-unit starting capacity can be permanently increased twice. The Matsuoka Override Manual (+50 units) is available in the Parlor for 6 Antique Coins.
The Matsuoka Master Manual (+50 units) is unlockable through the Special Content menu for 1,000 AP. Transfusion bags refill the collector on the go without exceeding the current maximum — carry them before boss sequences.
Leon already has every crafting recipe available — the ones he doesn't have yet unlock automatically as soon as he picks up a new weapon or material.
Picking up Gunpowder (Small) in the Logistics Warehouse 1F locker unlocks Handgun Ammo x10 crafting. Grabbing the Gal from the silver case unlocks Machine Gun Ammo x40.
Picking up the MSGB 500 in the Attic unlocks Shotgun Shells x3. Finding the first Hand Grenade in the Attic unlocks both Hand Grenade and Stacked Hand Grenade recipes.
Picking up the Classic 70 on the Roof unlocks Rifle Ammo x5.
Leon has no shared storage box. Every item he picks up takes a slot in his attaché case. When full, he must make decisions on the spot.
Supply boxes double as a pawn shop — sell weapons to free space and buy them back later when you have room. The practical fix: craft Gunpowder into ammunition the moment you pick it up.
The Ink Ribbon crafting recipe is unlocked after collecting your first Ink Ribbon Tin — but only on Standard and Insanity difficulties.
On Casual, Ink Ribbons cannot be crafted. If you're playing on Standard or Insanity and running low on saves, collect
Ink Ribbon Tins as a priority — they're your only route to additional save capability beyond finding loose Ink Ribbons in the environment.
| Name | Map Location | Details |
|---|---|---|
| Antique Coin ScrapARKAntique Coin Scrap | ARK | Found in the case on the cabinet. |
| Ink RibbonCare CenterInk Ribbon | Care Center | The Ink Ribbon Recipe is unlocked after you collect your first Ink Ribbon Tin. It is available only on Standard and Insanity difficulties. |
| Handgun Ammo x10East Raccoon CityHandgun Ammo x10 | East Raccoon City | Obtained automatically after picking up the Gunpowder (Small) in Logistics Warehouse 1F locker. |
| Machine Gun Ammo x40East Raccoon CityMachine Gun Ammo x40 | East Raccoon City | Obtained automatically after grabbing the Gal weapon from the silver case. |
| Molotov CocktailCare CenterMolotov Cocktail | Care Center | Found inside a case in the Bunkroom. |
| Mixed Herb (G+G)Care CenterMixed Herb (G+G) | Care Center | Obtained automatically through story progression in the Care Center. |
| Mixed Herb (G+G+G)Care CenterMixed Herb (G+G+G) | Care Center | Obtained automatically through story progression in the Care Center. |
| Makeshift KnifeCare CenterMakeshift Knife | Care Center | Obtained automatically through story progression in the Care Center. |
| ScrapCare CenterScrap | Care Center | Obtained automatically through story progression in the Care Center. |
| Handgun Ammo x8Care CenterHandgun Ammo x8 | Care Center | Unlocked by using the Blood Specimen (Denatured) on the Analyzer in the Blood Lab. |
| Hemolytic InjectorCare CenterHemolytic Injector | Care Center | Unlocked by using the Blood Specimen (Denatured) on the Analyzer in the Blood Lab. |
| Bottle of AcidARKBottle of Acid | ARK | Found in the case on the cabinet in the Monitor Control Room. |
| 12.7x55mm Ammo x2Care Center12.7x55mm Ammo x2 | Care Center | Obtained by using the Blood Specimen (Converged) on the Analyzer in the Blood Lab. Note: On Casual and Standard difficulties, the Converged Blood Specimen is found in the Waiting Room Closet, while on Insanity difficulty, it is found in the Records Room. |
| Med InjectorCare CenterMed Injector | Care Center | Obtained by using the Blood Specimen (Converged) on the Analyzer in the Blood Lab. Note: On Casual and Standard difficulties, the Converged Blood Specimen is found in the Waiting Room Closet, while on Insanity difficulty, it is found in the Records Room. |
| SteroidsCare CenterSteroids | Care Center | Obtained by using the Blood Specimen (Reversible) on the Analyzer in the Blood Lab. |
| StabilizerCare CenterStabilizer | Care Center | Obtained by using the Blood Specimen (Reversible) on the Analyzer in the Blood Lab. |
| Shotgun Shells x3Care CenterShotgun Shells x3 | Care Center | Automatically obtained after picking up the MSGB 500 weapon in the Attic. |
| Stacked Hand GrenadeCare CenterStacked Hand Grenade | Care Center | Automatically obtained after picking up your first Hand Grenade in the Attic. |
| Hand GrenadeCare CenterHand Grenade | Care Center | Automatically obtained after picking up your first Hand Grenade in the Attic. |
| Rifle Ammo x5Care CenterRifle Ammo x5 | Care Center | Obtained automatically when you get the Classic 70 on the Roof. |
| R.I.P. Knife (Insanity Difficulty Only)Care CenterR.I.P. Knife (Insanity Difficulty Only) | Care Center | Obtained by using the Blood Specimen (Polymerized) on the Analyzer in the Blood Lab. |
| Handgun Ammo x30 (Insanity Difficulty Only)Care CenterHandgun Ammo x30 (Insanity Difficulty Only) | Care Center | Obtained by using the Blood Specimen (Polymerized) on the Analyzer in the Blood Lab. |
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