Resident Evil Requiem: Blood Specimen Locations & Interactive Tracking Guide

Blood Specimens are Grace Ashcroft's research currency in Resident Evil Requiem — vials of biological data scattered through the Care Center that unlock her entire crafting system once analyzed.

There are 3 standard specimens across Casual and Standard difficulties, plus a fourth exclusive to Insanity mode.

Every specimen, its room location, difficulty tag, and the crafting recipes it unlocks are included on the Care Center interactive map — the checklist below tracks all five entries, including the Insanity variants.

What Are Blood Specimens in Resident Evil Requiem?

Blood Specimens are optional collectibles hidden throughout the Care Center. Collecting and analyzing them gives Grace access to powerful injectors, stronger ammo, and permanent upgrades.

This crafting system — called Hemocraft — requires Grace to use the Blood Collector to gather Infected Blood, which is then combined with the recipes unlocked by analyzing each specimen.

You can technically skip them, but doing so locks you out of Hemolytic Injectors, Med Injectors, Requiem Ammo, and the permanent Steroids and Stabilizer upgrades.

How to Analyze a Blood Specimen

Take each specimen to the Analyzer in the Blood Lab — there is a second Analyzer in the Office if needed.

Interact with it to start the analysis minigame: you see a chemical compound made of connected sphere and cube nodes.

The puzzle requires you to activate the correct nodes within a minimum number of steps — activating too many wrong moves can make it impossible to complete in the required count.

Each specimen has a specific minimum-step solution. Successfully analyzing any specimen for the first time unlocks the "Science!" trophy on PlayStation and the equivalent achievement on Xbox and PC.

All Three Standard Blood Specimens and What They Unlock

Blood Specimen (Denatured) — on the desk next to the Analyzer in the Blood Lab, available immediately when you first enter. This is the tutorial puzzle — activate the node between two other inactive nodes to complete it. Unlocks crafting for: Handgun Ammo and Hemolytic Injectors. Hemolytic Injectors are crucial for stealth approaches — they instantly incapacitate unaware enemies.

Blood Specimen (Reversible) — on the tray support in the room directly adjacent to the Blood Lab. Unlocks crafting for: Steroids (permanent max health increase) and the Stabilizer (permanent weapon damage and handling). Two of the most impactful permanent upgrades in Grace's arsenal.

Blood Specimen (Converged) — in the Waiting Room Closet on Casual and Standard. The minimum steps required for the analysis puzzle are two: select the middle cube of the three-cube chain, then activate the second cube from the end. Unlocks crafting for: Med Injectors and 12.7x55mm Ammo.

The 12.7x55mm rounds are specifically used for Leon's Requiem magnum — any unused ammo is returned to Leon when you hand the weapon back, so don't hold back on crafting it.

Level 1 Wristband: The Access Gate You Need First

The Reversible specimen's room requires the Level 1 Clearance Wristband to enter. Find it on a corpse in the hallway between the Lead Researcher's Office and the Conference Room.

The Converged specimen's Waiting Room Closet also requires Level 1 access. Collect the wristband before backtracking to the Blood Lab area — without it, two of the three standard specimens are out of reach.

Insanity Mode: The Polymerized Specimen

Insanity mode adds a fourth specimen not available on other difficulties: Blood Specimen (Polymerized), found on a table in the Waiting Room Closet. It unlocks crafting for the R.I.P. Knife — Insanity's exclusive melee weapon — and a batch of Handgun Ammo x30.

The Converged specimen also moves on Insanity, relocating from the Waiting Room Closet to the Records Room. Both Insanity-specific locations are tagged in the checklist below.

For the crafting system that uses these unlocked recipes, see the Crafting Recipe guide. For the Infected Blood required to actually craft, see the Infected Blood guide.

All locations are part of our Resident Evil Requiem guide hub.