Resident Evil Requiem: Safe Locations & Interactive Tracking Guide

There are 5 combination safes in Resident Evil Requiem — all opened during Grace Ashcroft's sections.


Opening every one unlocks the "No Safe is Safe" Bronze trophy. All locations, combinations, and rewards are pinned on MapMaster's maps, all accessible from the Resident Evil Requiem interactive guide hub.


All 5 Safe Combinations in Resident Evil Requiem


All codes work the same way: spin the dial left or right to the first number, reverse direction to the second, reverse again to the third, then press interact. If the dial snaps back to zero, you've missed a number or turned the wrong direction — restart from the beginning.


Bar & Lounge Safe (Care Center, 2F bar counter)


  • Casual/Standard: Left 10 – Right 80 – Left 30
  • Insanity: Right 20 – Left 50 – Right 30
  • Reward: Antique Coin x3


Examination Room Safe (Care Center, 1F East Wing shelf)


  • Casual/Standard: Right 30 – Left 10 – Right 50
  • Insanity: Left 50 – Right 30 – Left 90
  • Reward: Antique Coin x3


Basement Safe (Care Center Basement, small room outside Inspection)


  • Casual/Standard: Right 60 – Left 40 – Right 80
  • Insanity: Left 70 – Right 50 – Left 20
  • Reward: Raccoon Roundup Map (Rhodes Hill) + Handgun Ammo x10


Sterilization Chamber Safe (ARK, counter in corner)


  • Casual/Standard: Right 10 – Left 90 – Right 20
  • Insanity: Left 80 – Right 50 – Left 0
  • Reward: Molotov Cocktail + Med Injector + Handgun Ammo x15


Monitor Control Room Safe (ARK, cabinet at back of room)


  • Casual/Standard: Left 50 – Right 60 – Left 80
  • Insanity: Right 20 – Left 0 – Right 70
  • Reward: Empty Bottle + Bottle of Acid + Med Injector


You don't need to find the code file before using a combination — input any code directly on the dial when you locate the safe.


The Basement Safe: Why the Code Is Easy to Miss


The Basement Safe file isn't found during Grace's section. The clue is inside a cabinet in the Attic Storage room — a cabinet that only Leon can open with his Hatchet, after defeating Chunk in the Attic boss fight.


If you skip that cabinet as Leon, Grace cannot return to retrieve the file later. The file also counts toward the Case Closed trophy, making it doubly important.


Open the cabinet as Leon the moment the Attic fight ends — don't proceed to the next area first.


Insanity Difficulty: All Codes Change


On Insanity, every safe combination changes from Casual/Standard. The safe locations and their code files remain in the same places — only the numbers differ.


Insanity codes for all five safes are listed above and in each individual checklist entry below. The open Waiting Room safe (see below) is empty on Insanity.


The Open Waiting Room Safe


A sixth safe in the Waiting Room is already pried open when you arrive — no combination required.


On Casual and Standard, it contains Antique Coin x2. On Insanity, the safe is empty.

This safe does not count toward the "No Safe is Safe" trophy, but the coins are worth collecting during your first pass through the Waiting Room.


All 5 Safe Locations


  • Bar & Lounge — 2F bar counter, Care Center.
  • Examination Room — shelf to the right of the laid-out corpse, 1F East Wing, Care Center.
  • Basement — small room table outside the Inspection area, Care Center Basement.
  • Sterilization Chamber — counter in the corner of the room, ARK.
  • Monitor Control Room — cabinet at the back of the room, ARK.


All 5 Save locations are included on the Care Center area map and ARK interactive map, with both difficulty codes and full reward lists in the following list.

Name Details
Bar & Lounge SafeCare Center

Found on the bar counter in the Bar & Lounge room of the Care Center. The Safe Combination is provided by the Bar & Lounge Safe Code File found in the Care Center Office on the second floor.


Safe Combinations:

  • Casual & Standard Difficulties: Left 10 – Right 80 – Left 30
  • Insanity Difficulty: Right 20 – Left 50 – Right 30


Contains:

  • Antique Coin x3
Examination Room SafeCare Center

Found on a shelf in the Examination Room. The Safe Combination is provided by the Examination Room Safe Code File.


Safe Combinations:

  • Casual & Standard Difficulties: Right 30 – Left 10 – Right 50
  • Insanity Difficulty: Left 50 – Right 30 – Left 90


Contains:

  • Antique Coin x3
Basement SafeCare Center

Found on a table in a small room outside of Inspection. The Safe Combination is provided by the Basement Safe Code File.


Safe Combinations:

  • Casual & Standard Difficulties: Right 60 – Left 40 – Right 80
  • Insanity Difficulty: Left 70 – Right 50 – Left 20


Contains:

  • Raccoon Roundup Map (Rhodes Hill)
  • Handgun Ammo x10
Sterilization Chamber SafeARK

Found on the counter, in the corner of the room. The safe combination can be found on the Sterilization Chamber Safe File.


Safe Combinations:

  • Casual & Standard Difficulties: Right 10 – Left 90 – Right 20
  • Insanity Difficulty: Left 80 – Right 50 – Left 0


Contains:

  • Molotov Cocktail
  • Med Injector
  • Handgun Ammo x15
Monitor Control Room SafeARK

Found on the cabinet in the back of the room. The safe combination can be found on the Monitor Control Room Safe File.


Safe Combinations:

  • Casual & Standard Difficulties: Left 50 – Right 60 – Left 80
  • Insanity Difficulty: Right 20 – Left 0 – Right 70


Contains:

  • Empty Bottle
  • Bottle of Acid
  • Med Injector
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