Resident Evil Requiem: Safe Locations & Interactive Tracking Guide

In Resident Evil 9: Requiem, unlocking the game's high-tier resources and revealing hidden secrets depends on finding all Safe locations. Cracking these five security containers is the only way to earn the "No Safe is Safe" Trophy and claim essential items like Antique Coins and the Mr. Raccoon Map.

A critical detail for any run: all safes are found exclusively during Grace’s gameplay sections. Leon Kennedy does not encounter any safes during his tactical operations, making Grace the primary scavenger for these locked rewards.

Here are several tips you should consider while hunting these down:

Each safe requires you to spin the dial to the specific numbers. If the dial spins back to the default position, you have missed a number or turned the dial in the wrong direction.
While the solutions are found in Files scattered throughout the Care Center and ARK, you can input these codes immediately upon finding a safe to claim the rewards early.
The codes for Insanity Difficulty are completely different from those used in Casual/Standard runs. Verify your difficulty setting before attempting a combination.

Failing to secure a single safe is a critical oversight that can derail your 100% completion efforts. To eliminate any blind spots in your trophy hunt, the Map Master team has cataloged every vault combination and location within our Resident Evil 9: Requiem digital map guide.

Name	Map Location	Details
Bar & Lounge SafeCare CenterBar & Lounge Safe	Care Center	Found on the bar counter in the Bar & Lounge room of the Care Center. The Safe Combination is provided by the Bar & Lounge Safe Code File found in the Care Center Office on the second floor. Safe Combinations: Casual & Standard Difficulties: Left 10 – Right 80 – Left 30 Insanity Difficulty: Right 20 – Left 50 – Right 30 Contains: Antique Coin x3
Examination Room SafeCare CenterExamination Room Safe	Care Center	Found on a shelf in the Examination Room. The Safe Combination is provided by the Examination Room Safe Code File. Safe Combinations: Casual & Standard Difficulties: Right 30 – Left 10 – Right 50 Insanity Difficulty: Left 50 – Right 30 – Left 90 Contains: Antique Coin x3
Basement SafeCare CenterBasement Safe	Care Center	Found on a table in a small room outside of Inspection. The Safe Combination is provided by the Basement Safe Code File. Safe Combinations: Casual & Standard Difficulties: Right 60 – Left 40 – Right 80 Insanity Difficulty: Left 70 – Right 50 – Left 20 Contains: Raccoon Roundup Map (Rhodes Hill) Handgun Ammo x10
Sterilization Chamber SafeARKSterilization Chamber Safe	ARK	Found on the counter, in the corner of the room. The safe combination can be found on the Sterilization Chamber Safe File. Safe Combinations: Casual & Standard Difficulties: Right 10 – Left 90 – Right 20 Insanity Difficulty: Left 80 – Right 50 – Left 0 Contains: Molotov Cocktail Med Injector Handgun Ammo x15
Monitor Control Room SafeARKMonitor Control Room Safe	ARK	Found on the cabinet in the back of the room. The safe combination can be found on the Monitor Control Room Safe File. Safe Combinations: Casual & Standard Difficulties: Left 50 – Right 60 – Left 80 Insanity Difficulty: Right 20 – Left 0 – Right 70 Contains: Empty Bottle Bottle of Acid Med Injector

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