Resident Evil Requiem: Empty Bottle Locations & Interactive Tracking Guide

In Resident Evil 9: Requiem, the environment is your greatest weapon, and finding all Empty Bottle locations is the only way to capitalize on the game's throwable crafting system. For Grace Ashcraft, these glass containers are the essential housing for her biological warfare—transforming raw reagents and Infected Blood into lethal Molotov Cocktails and Acid Bottles.


Unlike standard ammo, Empty Bottles are finite world pickups. Missing a stash can leave you without the crowd control necessary to survive the swarms within the Care Center. Empty Bottles serve as the primary vessel for projectile crafting. Depending on your current research and the materials you've scavenged, these bottles can be turned into:


  • Molotov Cocktails: Created by combining 1x Empty Bottle and 60x Infected Blood. These are vital for incinerating flammable bio-organic threats.
  • Bottle of Acid: Crafted using 1x Empty Bottle and 80x Infected Blood. These deal massive damage to Lickers in the ARK.
  • Distraction Lures: In certain stealth segments, throwing an Empty Bottle at a hard surface is the only way to divert an enemy's attention and bypass a room without wasting munitions.


Because they are fragile items, bottles are usually hidden in storage areas, kitchens, or labs. On Casual and Standard difficulties, Empty Bottles are relatively plentiful. However, if you are playing on Insanity, their spawns are drastically reduced, and some are replaced by enemy drops. This makes every bottle you find a high-priority resource that should be hoarded for encounters where Leon's standard firearms struggle.


Because Empty Bottles are clear and often blend into the clutter of the Care Center, walking past them is easy. To prevent you from being caught without an explosive, the Map Master team has pinned every Empty Bottle location on our Interactive Resident Evil 9: Requiem Maps.


Our map guides provide precise screenshots of the more obscure bottles, helping you maximize your throwable inventory. Use the links in the table below to verify your scavenge and build the ultimate arsenal of glass-based weaponry.

Name Details
Empty BottleARK

Found on a counter in the Sterilization Chamber office.

Empty BottleARK

Found on a crate in a large container.

Empty BottleCare Center

Found next to the forklift in the Inspection area.

Empty BottleARK

Found on the desk in the Monitor Control Room.

Empty BottleARK

Found on the windowsill that you can reach by climbing on the Umbrella container in the Operations Room.

Empty BottleCare Center

Found on the table. You can collect it only after obtaining the Lighter.

Empty BottleCare Center

Found in the closet next to the sink.

Empty BottleCare Center

Found on a desk in the Care Center Office.

Empty BottleCare Center

Found on a shelf in the Care Center Dining Room. Hold on to this bottle to unlock a trophy later on.

Empty BottleCare Center

Found on the ground in the Nurses' Station Antechamber. You should pick it up the moment you reach the Care Center. This should be your first Empty Bottle because The Girl can smash it with her big feet.

Empty BottleCare Center

Found in a red case in the Boiler Room. It can be collected only after going through the Fence Hole and after interrupting the electricity.

Empty BottleARK

Found on a table in the Sterilization Chamber.

Empty BottleARK

Found a counter in the Sterilization Chamber.

Empty BottleARK

Found inside the Monitor Control Room Safe in the ARK.

Empty Bottle (Insanity Difficulty Only)Care Center

Found on the table in the Waiting Room Closet.

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